Au cours de mes \u00e9tudes de doctorat, je me suis concentr\u00e9e sur les chimioth\u00e9rapies contre le cancer qui s\u2019attaquent \u00e0 la tubuline en inhibant le comportement dynamique de cette prot\u00e9ine. La tubuline ayant un r\u00f4le \u00e0 jouer dans la division cellulaire, on peut supposer qu\u2019en interrompant celle-ci, on r\u00e9ussira \u00e0 freiner la croissance des cellules canc\u00e9reuses.<\/p>\n
La mise au point de nouveaux m\u00e9dicaments est indispensable \u00e0 la lutte contre le cancer. En ma qualit\u00e9 de chimiste-informaticienne, je fais appel aux principes de la m\u00e9canique classique et de la m\u00e9canique quantique afin de mesurer, \u00e0 l\u2019aide d\u2019ordinateurs, les structures et les propri\u00e9t\u00e9s des mol\u00e9cules, dans le but de mieux comprendre l\u2019action des m\u00e9dicaments sur la tubuline. Mes travaux permettent de concevoir de nouveaux candidats-m\u00e9dicaments plus efficaces, occasionnant moins d\u2019effets secondaires et capables de vaincre la pharmacor\u00e9sistance. La conception de m\u00e9dicaments assist\u00e9e par ordinateur est une m\u00e9thode de d\u00e9veloppement pharmaceutique fort int\u00e9ressante qui acc\u00e9l\u00e8re le processus de mise au point de m\u00e9dicaments et diminue les co\u00fbts associ\u00e9s aux m\u00e9thodes usuelles. J\u2019esp\u00e8re que mes recherches feront progresser les traitements de chimioth\u00e9rapie contre le cancer.<\/p>\n
Que signifie pour vous \u00eatre laur\u00e9at e d’une bourse Killam?<\/strong><\/u> Qu\u2019en avez-vous retir\u00e9?<\/strong><\/u> Pourquoi avoir choisi l\u2019universit\u00e9 de l’Alberta?<\/strong><\/u> Mes travaux permettent de concevoir de nouveaux candidats-m\u00e9dicaments plus efficaces, occasionnant moins d\u2019effets secondaires et capables de vaincre la pharmacor\u00e9sistance.<\/p>\n","protected":false},"featured_media":2622,"template":"","meta":{"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_links_to":"","_links_to_target":""},"categories":[116],"tags":[47],"class_list":["post-3004","scholars","type-scholars","status-publish","has-post-thumbnail","hentry","category-universite-dalberta","tag-chimie"],"featured_image_urls_v2":{"full":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB.jpg",712,447,false],"thumbnail":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB-150x150.jpg",150,150,true],"medium":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB-300x188.jpg",300,188,true],"medium_large":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB.jpg",712,447,false],"large":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB.jpg",712,447,false],"1536x1536":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB.jpg",712,447,false],"2048x2048":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB.jpg",712,447,false],"small-square":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB-217x217.jpg",217,217,true],"square-large":["https:\/\/killamlaureates.ca\/wp-content\/uploads\/2020\/07\/ChurchillWEB-500x447.jpg",500,447,true]},"post_excerpt_stackable_v2":"
\nC\u2019est un v\u00e9ritable honneur pour moi de voir mon travail r\u00e9compens\u00e9 par les Fiducies Killam, mises sur pied par Dorothy et Izaak Killam pour souligner les r\u00e9ussites scientifiques et scolaires de Canadiens. J\u2019accepte cette bourse avec honneur et humilit\u00e9 aux c\u00f4t\u00e9s d\u2019autres candidats talentueux.<\/p>\n
\nL\u2019aide financi\u00e8re des prestigieuses Fiducies Killam me permettra de mener des recherches de calibre mondial \u00e0 l\u2019Universit\u00e9 de l\u2019Alberta et de contribuer aux progr\u00e8s scientifiques dans mon domaine. Gr\u00e2ce \u00e0 elle, je pourrai me concentrer enti\u00e8rement sur mes recherches. Elle m\u2019offrira \u00e9galement la libert\u00e9 d\u2019effectuer des recherches et de poursuivre des projets sur des sujets qui m\u2019int\u00e9ressent.<\/p>\n
\nJ\u2019ai choisi de faire mon doctorat \u00e0 l\u2019Universit\u00e9 de l\u2019Alberta en raison de sa r\u00e9putation d\u2019excellence et parce qu\u2019elle est une des meilleures universit\u00e9s au Canada. Je pense aussi que, de par leur nature multidisciplinaire, mes recherches profiteront de l\u2019esprit de collaboration qui r\u00e8gne au sein de cette institution. L\u2019Universit\u00e9 de l\u2019Alberta offre aussi de nombreuses formules de financement, dont les bourses Killam,\u00a0 pour aider les candidats \u00e0 la ma\u00eetrise et au doctorat.<\/p>\n","protected":false},"excerpt":{"rendered":"